Primary Identifier | MGI:103258 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 21744 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA binding activity. Involved in spermatid development. Located in male germ cell nucleus. Is expressed in brain; genitourinary system; and sensory organ. Orthologous to human ADAD1 (adenosine deaminase domain containing 1). PHENOTYPE: Nullizygous mutations of this gene result in male infertility and abnormal spermiogenesis. Male mice homozygous for a null allele have show reduced sperm counts and motility, and increased sperm malformation resulting in background-dependent sterility. [provided by MGI curators] |