Primary Identifier | MGI:107422 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 18415 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATP binding activity and adenyl-nucleotide exchange factor activity. Predicted to be involved in protein folding and response to unfolded protein. Predicted to be located in cytoplasm. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; liver and biliary system; nervous system; and sensory organ. Orthologous to human HSPA4L (heat shock protein family A (Hsp70) member 4 like). PHENOTYPE: Mice homozygous for disruptions in this gene display increased incidence of male infertility, due to reduced number of mature sperm and reduced sperm motility, and hydronephrosis development. [provided by MGI curators] |