Primary Identifier | MGI:1918054 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 70804 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables heme binding activity and heme transmembrane transporter activity. Involved in heme transport. Is active in glutamatergic synapse. Is expressed in several structures, including central nervous system; neural retina; pharyngo-tympanic tube; and submandibular gland primordium. Orthologous to human PGRMC2 (progesterone receptor membrane component 2). PHENOTYPE: Mice homozygous for a conditional allele activated in the uterus exhibit early female reproductive senescence, decreased uterine NK cell number, increased endometrial gland number and uterine cysts. [provided by MGI curators] |