Primary Identifier | MGI:2448481 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 211666 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including glutathione binding activity; glutathione peroxidase activity; and glutathione transferase activity. Predicted to be involved in glutathione biosynthetic process; leukotriene biosynthetic process; and membrane lipid catabolic process. Predicted to be located in intracellular membrane-bounded organelle and plasma membrane. Predicted to be active in endoplasmic reticulum and nuclear envelope. Orthologous to human MGST2 (microsomal glutathione S-transferase 2). PHENOTYPE: Mice homozygous for a gene trap allele display resistance to induced ER stress related cell death and mortality. [provided by MGI curators] |