| Primary Identifier | MGI:109525 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 22066 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables inositol 1,4,5 trisphosphate binding activity and store-operated calcium channel activity. Acts upstream of or within gamma-aminobutyric acid secretion and oligodendrocyte differentiation. Located in caveola. Part of protein-containing complex. Is expressed in several structures, including brain; cochlea; ganglia; genitourinary system; and liver. Human ortholog(s) of this gene implicated in lung cancer. Orthologous to human TRPC4 (transient receptor potential cation channel subfamily C member 4). PHENOTYPE: Homozygous null mice exhibit a significant reduction in agonist-induced Ca2+ entry and vasorelaxation of aortic rings. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
