| Primary Identifier | MGI:1330861 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 13175 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein kinase activity. Involved in regulation of postsynapse assembly. Acts upstream of or within several processes, including generation of neurons; negative regulation of protein localization to nucleus; and peptidyl-serine phosphorylation. Located in postsynaptic density. Is active in glutamatergic synapse and postsynapse. Is expressed in several structures, including eye; future brain; genitourinary system; gut; and nervous system. Orthologous to human DCLK1 (doublecortin like kinase 1). PHENOTYPE: Mice homozygous for a null allele lack the corpus callosum and hippocampal commissure and show aberrant interhemispheric axonal projections. Mice homozygous for a different null allele have normal gross brain architecture but show axonal and dendritic defects following knockdown of Dcx expression. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
