Primary Identifier | MGI:92638 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 28146 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including endoplasmic reticulum unfolded protein response; positive regulation of organ growth; and positive regulation of peptide hormone secretion. Predicted to be located in cytoplasmic microtubule. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including jaw and orbito-sphenoid. Orthologous to human SERP1 (stress associated endoplasmic reticulum protein 1). PHENOTYPE: Targeted mutation results in postnatal growth retardation, decreased viablilty, impaired glucose tolerance, impaired growth hormone secretion and reduced size of some exocrine glands as well as exocrine gland target tissues [provided by MGI curators] |