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Protein Coding Gene : Siah2 siah E3 ubiquitin protein ligase 2
Primary Identifier  MGI:108062 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  20439
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables ubiquitin protein ligase activity. Involved in regulation of circadian rhythm and ubiquitin-dependent protein catabolic process. Predicted to be located in several cellular components, including early endosome; neuronal cell body; and nucleoplasm. Predicted to be active in cytoplasm. Is expressed in several structures, including bone; brain; gonad; hemolymphoid system gland; and sensory organ. Orthologous to human SIAH2 (siah E3 ubiquitin protein ligase 2).
PHENOTYPE: Mice homozygous for disruptions in this gene display an essentially normal phenotype. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-37099,
  • AA415433,
  • seven in absentia 2,
  • Sinh2,
  • siah E3 ubiquitin protein ligase 2,
  • MGI:2139578,
  • MGD-MRK-14421,
  • expressed sequence AA415433,
  • Siah2
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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