Primary Identifier | MGI:1921441 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 74191 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled purinergic nucleotide receptor activity. Acts upstream of or within cellular response to organic cyclic compound. Located in endoplasmic reticulum. Is expressed in immune system; intestine; male reproductive gland or organ; and skin. Orthologous to human P2RY13 (purinergic receptor P2Y13). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired bile flow, biliary cholesterol secretion, and bile acid secretion, decreased liver cholesterol level, and reduced macrophage-to-feces reverse cholesterol transport. [provided by MGI curators] |