| Primary Identifier | MGI:1919412 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 72162 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA helicase activity; histone deacetylase binding activity; and nucleic acid binding activity. Involved in several processes, including G-quadruplex DNA unwinding; positive regulation of cell differentiation; and positive regulation of macromolecule biosynthetic process. Acts upstream of or within response to exogenous dsRNA and response to virus. Located in cytosol. Is expressed in heart and telencephalon. Orthologous to human DHX36 (DEAH-box helicase 36). PHENOTYPE: Mice homozygous for a knock-out allele exhibit lethality around E7.0. Mice homozygous for a conditional allele activated in the hematopoiesis systemexhibit impaired erythropoiesis associated with cell cycle defect. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
