Primary Identifier | MGI:1914687 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 67437 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Is expressed in genitourinary system. Orthologous to human SSR3 (signal sequence receptor subunit 3). PHENOTYPE: Mice homozygous for a null mutation display neonatal lethality with growth retardation, reduced placental size and impaired placental vascular development. [provided by MGI curators] |