Primary Identifier | MGI:1341819 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 17349 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA binding activity. Involved in DNA-templated transcription and myeloid progenitor cell differentiation. Located in several cellular components, including ciliary basal body; motile cilium; and non-motile cilium. Is active in ciliary base. Is expressed in several structures, including brain; gonad; immune system; lung; and nasal cavity respiratory epithelium. Orthologous to human MLF1 (myeloid leukemia factor 1). PHENOTYPE: Mice homozygous for a null allele exhibit a slight increased B cells in the spleen and decreased ex vivo thymocyte apoptosis susceptibility. [provided by MGI curators] |