| Primary Identifier | MGI:1100848 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 16649 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables nuclear import signal receptor activity. Acts upstream of or within protein import into nucleus and response to hydrogen peroxide. Located in male germ cell nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human KPNA4 (karyopherin subunit alpha 4). PHENOTYPE: Mice homozygous for a null allele exhibit reduced male fertility. Sperm exhibit abnormal head morphologies, flagella with multiple axonemes, and malformed axoneme structures, and impaired acrosome reaction. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
