Primary Identifier | MGI:2683054 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 329679 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATPase inhibitor activity and protein-folding chaperone binding activity. Involved in intrinsic apoptotic signaling pathway in response to DNA damage. Acts upstream of or within with a positive effect on negative regulation of cell population proliferation. Located in cytoplasm. Orthologous to human FNIP2 (folliculin interacting protein 2). PHENOTYPE: Mice homozygous for a null allele have normal lifespans. Mice with combined loss of this gene and a single null allele of Fnip1 develop kidney cancer. [provided by MGI curators] |