Primary Identifier | MGI:2682211 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 381489 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables hormone binding activity. Acts upstream of or within several processes, including lung connective tissue development; myofibroblast differentiation; and nipple morphogenesis. Predicted to be active in plasma membrane. Is expressed in brain; mandibular process; metanephros; and oral region epithelium. Orthologous to human RXFP1 (relaxin family peptide receptor 1). PHENOTYPE: Mice homozygous for disruptions in this gene display reduced male fertility, particularly at younger ages and early generations. Impaired nipple development prevents nursing by females. [provided by MGI curators] |