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Protein Coding Gene : Rxfp1 relaxin/insulin-like family peptide receptor 1

Primary Identifier  MGI:2682211 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  381489
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables hormone binding activity. Acts upstream of or within several processes, including lung connective tissue development; myofibroblast differentiation; and nipple morphogenesis. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in brain and metanephros. Orthologous to human RXFP1 (relaxin family peptide receptor 1).
PHENOTYPE: Mice homozygous for disruptions in this gene display reduced male fertility, particularly at younger ages and early generations. Impaired nipple development prevents nursing by females. [provided by MGI curators]
  • synonyms:
  • relaxin/insulin-like family peptide receptor 1,
  • Rxfp1,
  • Lgr7,
  • LOC381489,
  • MGI:2685864,
  • Gm1018,
  • leucine-rich repeat-containing G protein-coupled receptor 7,
  • gene model 1018, (NCBI)

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For