| Primary Identifier | MGI:95751 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 14658 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables extracellularly glycine-gated chloride channel activity; glycine binding activity; and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Acts upstream of or within several processes, including adult walking behavior; gamma-aminobutyric acid receptor clustering; and righting reflex. Located in GABA-ergic synapse; dendrite; and membrane. Is active in glycinergic synapse. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and skeleton. Used to study hyperekplexia 2. Human ortholog(s) of this gene implicated in hyperekplexia 2. Orthologous to human GLRB (glycine receptor beta). PHENOTYPE: Mutations in this gene result in a neurological disorder and premature death. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
