| Primary Identifier | MGI:108078 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 20319 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables Wnt-protein binding activity; endopeptidase activator activity; and receptor ligand activity. Involved in several processes, including branching involved in blood vessel morphogenesis; regulation of Wnt signaling pathway; and regulation of macromolecule metabolic process. Acts upstream of or within several processes, including chordate embryonic development; negative regulation of signal transduction; and regulation of endopeptidase activity. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; eye; and genitourinary system. Orthologous to human SFRP2 (secreted frizzled related protein 2). PHENOTYPE: Mice homozygous for a null allele exhibit background-sensitive syndactyly. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
