Primary Identifier | MGI:1924165 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 76915 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable double-stranded DNA binding activity. Predicted to be involved in homologous chromosome pairing at meiosis and reciprocal meiotic recombination. Predicted to be located in nucleus. Is expressed in branchial arch; central nervous system; embryo; forelimb bud; and somite. Orthologous to human MND1 (meiotic nuclear divisions 1). PHENOTYPE: Homozygous mutants for this allele display defects in homologous chromosome synapsis and double-strand break repair. [provided by MGI curators] |