Primary Identifier | MGI:2441869 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 213498 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled receptor binding activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including Rho protein signal transduction; positive regulation of DNA-templated transcription; and positive regulation of L-glutamate import across plasma membrane. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including cardiovascular system; facial prominence ectoderm; genitourinary system; gut; and nervous system. Orthologous to human ARHGEF11 (Rho guanine nucleotide exchange factor 11). PHENOTYPE: Mice homozygous for a knock-out allele exhibit no obvious phenotype. [provided by MGI curators] |