Primary Identifier | MGI:2180167 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 246703 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity. Predicted to be involved in several processes, including membrane raft distribution; negative regulation of angiogenesis; and regulation of cholesterol efflux. Located in several cellular components, including cell body; extracellular space; and mitochondrion. Is expressed in several structures, including genitourinary system; gut; nervous system; respiratory system; and skeletal muscle tissue. Orthologous to human NAXE (NAD(P)HX epimerase). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased developmental retinal angiogenesis and show pathological neovascularization in a murine hindlimb ischemia model. [provided by MGI curators] |