Primary Identifier | MGI:1927379 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 58176 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ammonium channel activity. Involved in ammonium transmembrane transport. Located in basolateral plasma membrane. Is expressed in genitourinary system. Orthologous to human RHBG (Rh family B glycoprotein). PHENOTYPE: Mice homozygous for a knock-out allele are viable, do not develop hyperammonemic hepatic encephalopathy or distal tubular acidosis, and show a normal renal response to chronic acid-loading and no changes in NH4+ or NH3 entry across the basolateral membrane of cortical collecting ducts cells. [provided by MGI curators] |