| Primary Identifier | MGI:1919163 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 71913 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity. Involved in several processes, including epithelial cell maturation; establishment of skin barrier; and positive regulation of epidermis development. Acts upstream of or within cornification; cuticle development; and hair follicle morphogenesis. Located in lysosomal membrane and trans-Golgi network membrane. Is expressed in alimentary system; genitourinary system; naris; skin; and thymus. Used to study atopic dermatitis. Orthologous to human TMEM79 (transmembrane protein 79). PHENOTYPE: Mice homozygous for a spontaneous mutation exhibit abnormal coat/hair pigmentation, abnormal zigzag hair morphology, and a more sparse and shiny coat than wild-type controls. Some adults display a mild irritation around the eyes. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
