Primary Identifier | MGI:1932697 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 83409 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to contribute to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Acts upstream of or within several processes, including fibroblast migration; positive regulation of MAPK cascade; and regulation of cell-substrate junction organization. Located in late endosome. Orthologous to human LAMTOR2 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 2). PHENOTYPE: Embryos homozygous for a knock-out allele display severe developmental defects, are growth retarded and die prior to E10.5. [provided by MGI curators] |