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Protein Coding Gene : Clk2 CDC-like kinase 2

Primary Identifier  MGI:1098669 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  12748
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables protein serine/threonine kinase activity and protein tyrosine kinase activity. Involved in negative regulation of gluconeogenesis and protein autophosphorylation. Acts upstream of or within peptidyl-tyrosine phosphorylation and response to retinoic acid. Located in nucleus. Is expressed in several structures, including brain; genitourinary system; liver; retina; and thyroid gland. Orthologous to human CLK2 (CDC like kinase 2).
PHENOTYPE: Mice homozygous for a conditional allele activated in the liver exhibit decreased hepatic fatty acid oxidation and ketogenesis. [provided by MGI curators]
  • synonyms:
  • MGI:2139908,
  • CDC-like kinase 2,
  • AU041688,
  • Clk2,
  • expressed sequence AU041688

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For