| Primary Identifier | MGI:2441670 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 229534 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables transcription coactivator activity. Acts upstream of or within several processes, including articular cartilage development; extracellular matrix organization; and positive regulation of chondrocyte proliferation. Located in chromatin; cytoplasm; and nucleus. Part of transcription regulator complex. Is expressed in brain; diaphragm; gut; heart ventricle; and spinal cord ventricular layer. Orthologous to human PBXIP1 (PBX homeobox interacting protein 1). PHENOTYPE: Mice homozygous for a null allele exhibit proportional dwafism. Mice homozygous for a conditional allele activated in chondrocytes exhibit improved induced pathogenic osteoarthritis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
