| Primary Identifier | MGI:2153183 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 140493 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calmodulin binding activity; inward rectifier potassium channel activity; and small conductance calcium-activated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Located in cytoplasm and plasma membrane. Is expressed in brain; early conceptus; and heart. Human ortholog(s) of this gene implicated in paranoid schizophrenia and schizophrenia. Orthologous to human KCNN3 (potassium calcium-activated channel subfamily N member 3). PHENOTYPE: Mice homozygous for an insertion of a tetracycline-regulated gene switch display no overt phenotype when expression is abolished by doxycycline treatment; in contrast, untreated homozygotes show abnormal respiratory responses to hypoxia, impaired parturition, and pregnancy-related premature death. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
