Primary Identifier | MGI:1917343 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 70093 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ubiquitin conjugating enzyme activity. Acts upstream of or within several processes, including embryo implantation; prolactin secretion; and suckling behavior. Predicted to be located in cytosol and filopodium. Predicted to be active in nucleus. Is expressed in several structures, including 4-cell stage embryo; blastocyst; mammary gland; reproductive system; and spleen. Orthologous to human UBE2Q1 (ubiquitin conjugating enzyme E2 Q1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit female-specific pleiotropic reproductive defects and partial embryonic lethality at implantation. [provided by MGI curators] |