Primary Identifier | MGI:1927232 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 68328 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTP binding activity; GTPase activity; and protein kinase A catalytic subunit binding activity. Involved in endocytic recycling; endothelial cell chemotaxis; and protein localization to cell leading edge. Located in several cellular components, including bicellular tight junction; endocytic vesicle; and lamellipodium. Is expressed in several structures, including brain; early conceptus; meninges; secondary oocyte; and small intestine. Orthologous to human RAB13 (RAB13, member RAS oncogene family). PHENOTYPE: Mice homozygous for a knock-out allele are viable and grow normally but exhibit hypoplastic lymphoid tissues caused by impaired lymphocyte trafficking capacity. [provided by MGI curators] |