Primary Identifier | MGI:1353474 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 30791 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables zinc ion transmembrane transporter activity. Acts upstream of or within chordate embryonic development; limb development; and zinc ion transport. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human SLC39A1 (solute carrier family 39 member 1). PHENOTYPE: On a zinc-adequate diet, homozygous null mutant mice exhibit normal fertility and normal embryonic and postnatal development. E14 embryos of dams fed a zinc-deficient diet from day E8 have <3.3-fold the incidence of abnormalities seen in wild-type embryos of zinc-deprived wild-type mothers. [provided by MGI curators] |