Primary Identifier | MGI:1913761 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 66511 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable methyl-CpG binding activity. Acts upstream of or within in utero embryonic development. Predicted to be located in nucleolus. Predicted to be part of transcription export complex. Predicted to be active in nuclear speck. Is expressed in several structures, including alimentary system; dorsal root ganglion; integumental system; olfactory epithelium; and thymus. Orthologous to human CHTOP (chromatin target of PRMT1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit a hypocellular placenta, abnormal placental labyrinth vasculature morphology, abnormal spongiotrophoblast inclusions, double outlet right ventricle, and partial lethality throughout fetal growth and development. [provided by MGI curators] |