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Protein Coding Gene : S100a1 S100 calcium binding protein A1

Primary Identifier  MGI:1338917 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  20193
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable several functions, including ATPase binding activity; S100 protein binding activity; and protein homodimerization activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; positive regulation of nitric-oxide synthase activity; and positive regulation of sprouting angiogenesis. Located in sarcoplasmic reticulum. Is expressed in several structures, including brain; heart; inner ear; musculature; and urothelium. Orthologous to human S100A1 (S100 calcium binding protein A1).
PHENOTYPE: Homozygous and heterozygous mice exhibit a reduced cardiac contractility in response to chronic hemodynamic stress. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI266795,
  • S100 calcium binding protein A1,
  • MGI:2139656,
  • S100,
  • AI266795,
  • S100a1,
  • S100a

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For