| Primary Identifier | MGI:96816 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 16939 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) A structural constituent of cytoskeleton and structural constituent of skin epidermis. Predicted to be involved in keratinocyte differentiation and peptide cross-linking. Located in cytoplasmic side of plasma membrane. Is active in cornified envelope. Is expressed in several structures, including alimentary system; male reproductive system; sensory organ; skin; and thymus. Orthologous to human LORICRIN (loricrin cornified envelope precursor protein). PHENOTYPE: Mice homozygous for disruptions in this gene are runted at birth, have a translucent skin and skin skin barrier defect. The morphological skin phenotype disappears after 4-5 days. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
