Primary Identifier | MGI:1920981 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 433619 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be located in cytoplasm. Orthologous to human KPRP (keratinocyte proline rich protein). PHENOTYPE: Mice heterozygous for a null allele show a thin stratum granulosum, detachment of lower layers of the stratum corneum, abnormal desmosome structure and enhanced percutaneous immune responses to irritants and allergens. Homozygotes show a similar phenotype as heterozygotes. [provided by MGI curators] |