| Primary Identifier | MGI:1923992 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 76742 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calcium-dependent protein binding activity; ionotropic glutamate receptor binding activity; and phosphatidylinositol-3-phosphate binding activity. Involved in regulation of postsynaptic membrane neurotransmitter receptor levels. Acts upstream of or within endosomal transport. Located in endosome. Is active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and postsynaptic endosome. Is expressed in several structures, including adipose tissue; eye; genitourinary system; gut; and nervous system. Orthologous to human SNX27 (sorting nexin 27). PHENOTYPE: Mice homozygous for a knock-out allele exhibit prenatal and postnatal lethality, decreased organ size, slow postnatal weight gain, and decreased endocytosis of Grin2c. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
