Primary Identifier | MGI:1927237 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 70737 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables microtubule binding activity. Acts upstream of or within bicellular tight junction assembly; epithelial cell morphogenesis; and microtubule cytoskeleton organization. Located in bicellular tight junction and brush border. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; pituitary gland; and respiratory system. Orthologous to human CGN (cingulin). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased sensitivity to the ulcerogenic action of cysteamine. [provided by MGI curators] |