Primary Identifier | MGI:1355285 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 50874 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables tropomyosin binding activity. Predicted to be involved in actin filament organization; muscle contraction; and myofibril assembly. Located in striated muscle thin filament. Is expressed in diaphragm; liver; lung; and vertebral axis musculature. Orthologous to human TMOD4 (tropomodulin 4). PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and exhibit no overt myopathy, with normal thin filament lengths, myofibril organization, and skeletal muscle contractile function. [provided by MGI curators] |