Primary Identifier | MGI:1915231 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 67981 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in several processes, including meiosis I cell cycle process; meiotic sister chromatid cohesion; and regulation of cell cycle process. Acts upstream of or within homologous chromosome pairing at meiosis. Located in cytoplasm and synaptonemal complex. Is expressed in several structures, including gonad. Orthologous to human HORMAD1 (HORMA domain containing 1). PHENOTYPE: Homozgous mice are infertile because of meiosis arrest associated with impaired synaptonemal-complex formation. [provided by MGI curators] |