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Protein Coding Gene : Plekho1 pleckstrin homology domain containing, family O member 1
Primary Identifier  MGI:1914470 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  67220
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Acts upstream of or within several processes, including lamellipodium morphogenesis; myoblast fusion; and myoblast migration. Located in muscle cell projection membrane and ruffle membrane. Orthologous to human PLEKHO1 (pleckstrin homology domain containing O1).
PHENOTYPE: Mice homozygous for a null allele exhibit age-dependent increase in bone volume and increased osteoblast activity. [provided by MGI curators]
  • synonyms:
  • Jza2,
  • JZA-20,
  • RIKEN cDNA 2810052M02 gene,
  • Plekho1,
  • MGD-MRK-35895,
  • MGI:107424,
  • pleckstrin homology domain containing, family O member 1,
  • Jun zipper-associated 2,
  • CKIP-1,
  • 2810052M02Rik
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2 Involved In Mutations

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