Primary Identifier | MGI:891965 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 22365 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Located in Golgi membrane and endosome membrane. Human ortholog(s) of this gene implicated in severe congenital neutropenia 5. Orthologous to human VPS45 (vacuolar protein sorting 45 homolog). PHENOTYPE: A knock-out allele shows embryonic lethality around 7.5, with impaired germ layer formation. [provided by MGI curators] |