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Protein Coding Gene : Fcgr1 Fc receptor, IgG, high affinity I
Primary Identifier  MGI:95498 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  14129
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables IgG binding activity and IgG receptor activity. Acts upstream of or within several processes, including antibody-dependent cellular cytotoxicity; endocytosis; and positive regulation of hypersensitivity. Located in external side of plasma membrane. Is expressed in liver. Orthologous to several human genes including FCGR1A (Fc gamma receptor Ia).
PHENOTYPE: Homozygous mutation of this gene results immune response defects including a decreased inflammatory response. [provided by MGI curators]
  • synonyms:
  • CD64,
  • Fcgr1,
  • FcgammaRI,
  • AV092959,
  • MGI:2139673,
  • expressed sequence AV092959,
  • expressed sequence AI323638,
  • AI323638,
  • MGD-MRK-9732,
  • MGI:2139933,
  • Fc receptor, IgG, high affinity I
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Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

10 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

3 Driver For





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