| Primary Identifier | MGI:1913126 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 229615 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables SUMO transferase activity. Acts upstream of or within several processes, including negative regulation of macromolecule biosynthetic process; negative regulation of osteoclast differentiation; and protein sumoylation. Located in cytoplasm and nucleus. Is active in glutamatergic synapse; postsynaptic cytosol; and presynaptic cytosol. Is expressed in several structures, including blastocyst; central nervous system; eye; genitourinary system; and maxillary process. Orthologous to human PIAS3 (protein inhibitor of activated STAT 3). PHENOTYPE: Mice homozygous for a null allele display decreased susceptibility to induced abdominal aortic aneurysm formation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
