| Primary Identifier | MGI:2444594 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 320718 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables chloride channel activity; chloride:bicarbonate antiporter activity; and identical protein binding activity. Involved in monoatomic anion transport. Acts upstream of or within bicarbonate transport; chloride transport; and regulation of pH. Located in apical plasma membrane. Is expressed in adrenal gland; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in gastrointestinal system disease. Orthologous to human SLC26A9 (solute carrier family 26 member 9). PHENOTYPE: Mice homozygous for a null allele exhibit reduced gastric secretory membranes and loss of gastric acid secretion. [provided by MGI curators] |