Primary Identifier | MGI:1310004 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 14263 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable N,N-dimethylaniline monooxygenase activity and aldehyde oxidase activity. Involved in regulation of cholesterol metabolic process. Predicted to be located in cytosol and endoplasmic reticulum. Is expressed in bladder. Orthologous to human FMO5 (flavin containing dimethylaniline monoxygenase 5). PHENOTYPE: Mice homozygous for a knock-out allele show an age-related lean phenotype despite increased food intake, lower plasma levels of glucose and cholesterol, decreased fat storage in WAT, altered fatty acid oxidation, increased energy expenditure and respiratory quotient but normal physical activity. [provided by MGI curators] |