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Protein Coding Gene : Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
Primary Identifier  MGI:96235 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  15494
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable 3-beta-hydroxy-delta5-steroid dehydrogenase (NAD+) activity and steroid delta-isomerase activity. Predicted to be involved in C21-steroid hormone biosynthetic process; androgen biosynthetic process; and negative regulation of iron ion transport. Located in mitochondrial inner membrane. Is expressed in adrenal gland; embryo; liver; testis; and testis medullary region. Human ortholog(s) of this gene implicated in hypertension and hypospadias. Orthologous to human HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1) and HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2).
  • synonyms:
  • MGD-MRK-10948,
  • RIKEN cDNA 9030618K22 gene,
  • Hsd3b3,
  • MGI:2139796,
  • expressed sequence AI790201,
  • MGI:1918777,
  • 9030618K22Rik,
  • AI790201,
  • hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
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