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Protein Coding Gene : Igsf3 immunoglobulin superfamily, member 3
Primary Identifier  MGI:1926158 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  78908
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to be involved in lacrimal gland development. Predicted to be active in membrane. Is expressed in dorsal root ganglion; lung; and spinal cord. Human ortholog(s) of this gene implicated in lacrimal duct obstruction. Orthologous to human IGSF3 (immunoglobulin superfamily member 3).
PHENOTYPE: Homozygous null mice show reduced migration of vagal neural crest cells and impaired development of the enteric nervous system, with defects in formation of the muscularis externa and disorganized innervation of the enteric villi in the small intestine. [provided by MGI curators]
  • synonyms:
  • immunoglobulin superfamily, member 3,
  • RIKEN cDNA 2810035F16 gene,
  • 4833439O17Rik,
  • 1700016K10Rik,
  • MGI:1922800,
  • Igsf3,
  • RIKEN cDNA 4833439O17 gene,
  • mKIAA0466,
  • RIKEN cDNA 1700016K10 gene,
  • 2810035F16Rik,
  • MGI:1919956
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