Primary Identifier | MGI:92356 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 229663 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RISC complex binding activity. Predicted to be involved in IRES-dependent viral translational initiation; regulation of gene expression; and stress granule assembly. Located in mitochondrial inner membrane. Is expressed in several structures, including limb; liver; lung; small intestine; and testis. Orthologous to human CSDE1 (cold shock domain containing E1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic growth retardation, delayed heart development, absence of neural tube closure, and complete embryonic lethality during organogenesis associated with placental developmental defects. [provided by MGI curators] |