| Primary Identifier | MGI:1928743 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 56543 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable A-type (transient outward) potassium channel activity and transmembrane transporter binding activity. Predicted to contribute to voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization. Predicted to be involved in several processes, including cellular response to BMP stimulus; potassium ion transmembrane transport; and regulation of heart rate by cardiac conduction. Located in membrane. Part of voltage-gated potassium channel complex. Is active in GABA-ergic synapse and postsynaptic specialization membrane. Is expressed in heart and heart ventricle. Human ortholog(s) of this gene implicated in Brugada syndrome 9 and spinocerebellar ataxia type 19/22. Orthologous to human KCND3 (potassium voltage-gated channel subfamily D member 3). PHENOTYPE: Mice homozygous for a reporter (null) allele are viable and fertile and exhibit normal cardiac morphology and function. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
