| Primary Identifier | MGI:1858415 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 53975 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables histone deacetylase binding activity and protein-macromolecule adaptor activity. Involved in positive regulation of apoptotic process. Acts upstream of or within negative regulation of transcription by RNA polymerase II; oogenesis; and regulation of steroid biosynthetic process. Part of RNA polymerase II transcription repressor complex. Is expressed in several structures, including brain; branchial arch; genitourinary system; hemolymphoid system; and liver. Orthologous to human DDX20 (DEAD-box helicase 20). PHENOTYPE: Mice homozygous for a null allele fail to implant and develop past the 2-cell stage. Heterozygous null females are viable, healthy and fertile but show increased ovary weight, a greater number of empty follicles, a prolonged estrous phase, and reduced nocturnal and stress-induced serum ACTH levels. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
