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Protein Coding Gene : Chia1 chitinase, acidic 1

Primary Identifier  MGI:1932052 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  81600
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables chitin binding activity and chitinase activity. Involved in chitin catabolic process. Located in cytoplasm. Is expressed in choroid plexus; lung; and nervous system. Human ortholog(s) of this gene implicated in asthma. Orthologous to human CHIA (chitinase acidic).
PHENOTYPE: Homozygous knockout causes increased neutrophil and lymphocyte counts in bronchoalveolar lavage in certain pulmonary allergen exposure experiments, but immune response to various pulmonary allergen exposures is unchanged. [provided by MGI curators]
  • synonyms:
  • MGI:1913535,
  • Chia,
  • chitinase, acidic 1,
  • RIKEN cDNA 2200003E03 gene,
  • 2200003E03Rik,
  • Chia1,
  • chitinase, acidic,
  • YNL,
  • AMCase

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

2 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For